Highly catalysis MOF Ce supported Ag nanoclusters coupled with specific aptamer for SERS quantitative assay of trace dopamine

A cerium metal organic framework-loaded silver nanocluster (MOF ) is synthesized by a facile stirring procedure with trimesic acid, cerium nitrate, silver nitrate and NaBH , which exhibites strong catalytic activity in the indicated reaction of HAuCl -sodium lactate (SL). MOF can sensitively detect...

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Bibliographic Details
Published inTalanta (Oxford) Vol. 245; p. 123468
Main Authors Shi, Jinling, Li, Jingjing, Liang, Aihui, Jiang, Zhiliang
Format Journal Article
LanguageEnglish
Published Netherlands 01.08.2022
Subjects
SERS quantitative Analysis
Apt
Nanocatalysis
MOF-Loaded silver nanoclusters
Dopamin
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Summary:A cerium metal organic framework-loaded silver nanocluster (MOF ) is synthesized by a facile stirring procedure with trimesic acid, cerium nitrate, silver nitrate and NaBH , which exhibites strong catalytic activity in the indicated reaction of HAuCl -sodium lactate (SL). MOF can sensitively detect dopamine (DA) by surface-enhanced Raman scattering (SERS) and resonance Rayleigh scattering (RRS) techniques with a detection concentration range of 0.01-0.25 nmol/L and a detection limit of 0.008 nmol/L. Based on the specific binding of aptamer (Apt)-DA and the catalytic amplification strategy of MOF on HAuCl -SL, a sensitive and convenient DA platform for dual-mode detection of SERS and RRS is constructed. In addition, the platform is successfully applied to detect DA in human serum with satisfactory recoveries (95.7-102%).
ISSN:1873-3573