When necrosis threatens the kidney patient

Calciphylaxis is a rare but devastating condition characterized by a calcifying thrombosing microangiopathy resulting in painful necrotic skin lesions. Risk factors are multiple, the most important being obesity, disorders of phosphocalcic metabolism and acenocoumarol. Largely unknown by the medical...

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Bibliographic Details
Published inRevue médicale suisse Vol. 17; no. 727; p. 394
Main Authors Ackermann, Mélanie, Humbert, Antoine, Stucker, Fabien
Format Journal Article
LanguageFrench
Published Switzerland 24.02.2021
Subjects
Biopsy
Calciphylaxis - diagnosis
Calciphylaxis - etiology
Female
Humans
Kidney
Necrosis
Pregnancy
Vascular Diseases
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Summary:Calciphylaxis is a rare but devastating condition characterized by a calcifying thrombosing microangiopathy resulting in painful necrotic skin lesions. Risk factors are multiple, the most important being obesity, disorders of phosphocalcic metabolism and acenocoumarol. Largely unknown by the medical community, its pathogenesis is still incompletely elucidated; its diagnosis by skin biopsy remains difficult and increasingly debated because potentially associated with an aggravation of lesions. Its treatment must be as premature as possible andmultimodal. However, the results are up to now unsatisfactory, as specific treatment of calciphylaxis does not yet exist.
ISSN:1660-9379