Relevance of quantification in brain PET studies with 18 F-FDG

The inclusion of F-FDG PET as a biomarker in the diagnostic criteria of neurodegenerative diseases and its indication in the presurgical assessment for drug-resistant epilepsies allow to improve specificity of these diagnosis. The traditional interpretation of neurological PET studies has been perfo...

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Bibliographic Details
Published inRevista espanola de medicina nuclear e imagen molecular Vol. 39; no. 3; p. 184
Main Authors Niñerola-Baizán, A, Aguiar, P, Cabrera-Martín, M N, Vigil, C, Gómez-Grande, A, Lorenzo, C, Rubí, S, Sopena, P, Camacho, V
Format Journal Article
LanguageEnglish
Published Spain 01.05.2020
Subjects
Cuantificación
Brain
Epilepsia
Epilepsy
Cerebro
18F-FDG
F-FDG
Demencia
PET
Dementia
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Summary:The inclusion of F-FDG PET as a biomarker in the diagnostic criteria of neurodegenerative diseases and its indication in the presurgical assessment for drug-resistant epilepsies allow to improve specificity of these diagnosis. The traditional interpretation of neurological PET studies has been performed qualitatively, although in the last decade, several quantitative evaluation methods have emerged. This technical development has become relevant in clinical practice, improving specificity, reproducibility and reducing the interrater reliability derived from visual analysis. In this article we update/review the main imaging processing techniques currently used. This may allow the Nuclear Medicine physician to know their advantages and disadvantages when including these procedures in daily clinical practice.
ISSN:2253-8070