Outcome of acute renal failure in subjects with HIV living in Abidjan, Ivory Coast over the period 1 st January 2014 to 31 st December 2017

In Ivory Coast, the prevalence of human immunodeficiency virus (HIV) infection is high. Any organ can be affected, in particular the kidney. Some studies conducted in Ivory Coast highlighted that opportunistic infections are a poor prognostic factors for acute renal failure (ARF). The purpose of thi...

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Published inThe Pan African medical journal Vol. 34; p. 2
Main Authors Guei, Monlet Cyr, Sidibé, Marthe, Wognin, Anastasie, Konan, Serge Didier, Choho, Motochi Carole, Yao, Hubert Kouamé, Ackoundou-N'guessan, Clément, Gnionsahé, Appolinaire Daze
Format Journal Article
LanguageFrench
Published Uganda 2019
Subjects
Acute Kidney Injury - epidemiology
Acute Kidney Injury - virology
Adolescent
Adult
Aged
CD4 Lymphocyte Count
Cote d'Ivoire - epidemiology
Female
HIV Infections - complications
HIV Infections - virology
Humans
Male
Middle Aged
Obesity - epidemiology
Prevalence
Prognosis
Retrospective Studies
Risk Factors
Sex Factors
Young Adult
Cote d'Ivoire
acute renal failure
Disease outcome
Ivory Coast
HIV infection
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Summary:In Ivory Coast, the prevalence of human immunodeficiency virus (HIV) infection is high. Any organ can be affected, in particular the kidney. Some studies conducted in Ivory Coast highlighted that opportunistic infections are a poor prognostic factors for acute renal failure (ARF). The purpose of this study was to investigate the other possible factors associated with ARF outcome among subjects with HIV infection. We conducted a retrospective analytical study, at the University Hospital Center of Yopougon over the period January 2014-December 2017. All patients over the age of 18 years with HIV infection associated with ARF were enrolled. The study included 73 patients, reflecting a rate of 24%. The average age of patients was 39.32 ± 10.50 years, ranging from 18 to 65 years. Sex ratio of 1.6 favoured women. Obesity (p=0.047; OR=8.72; CI (95%)=1.07-39.21) and CD4 count < 200/mm (p=0.000; OR=58.50; IC (95%)=10.31-55.12) were associated with poor prognosis of ARF. In Ivory Coast, the hospital prevalence of ARF in patients with HIV is high. Unfavorable outcome included death or chronicity. In addition to deep immunosuppression already known as a poor prognostic factor, this study showed that obesity is associated with unfavorable outcome of ARF in subjects with HIV.
ISSN:1937-8688