The comparative evaluation of components used in development of immune chromatographic test-systems

The article summarizes data of research studies concerning searching optimal conditions of development of highly specific and highly sensitive immune chromatography test-systems designed for detection of agents of infectious diseases. The analysis was implemented concerning choosing of optimal size...

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Bibliographic Details
Published inKlinicheskaia laboratornaia diagnostika Vol. 62; no. 1; p. 30
Main Authors Smirnova, D N, Krupina, K A, Bogacheva, N V, Darmov, I V
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.01.2017
Subjects
Antibodies - immunology
Chromatography
Communicable Diseases - diagnosis
Communicable Diseases - immunology
Gold Colloid - chemistry
Humans
Immunoconjugates - immunology
Immunoconjugates - isolation & purification
Membranes, Artificial
Nanoparticles - chemistry
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Summary:The article summarizes data of research studies concerning searching optimal conditions of development of highly specific and highly sensitive immune chromatography test-systems designed for detection of agents of infectious diseases. The analysis was implemented concerning choosing of optimal size of nano-particles of colloid gold and concentration of antibodies for production of conjugate. The alternatives are presented concerning the most frequently used combinations of buffer solutions applied for development and analysis of immune chromatography test-systems. The preferences are established in the field of characteristics of membranes used in composition of multi-membrane composite of immune chromatographic test-systems.
ISSN:0869-2084