The ABCB1, CYP2C19, CYP3A5 and CYP4F2 genetic polymorphisms and platelet reactivity in the early phases of acute coronary syndromes

• Published in: Drug metabolism and personalized therapy Vol. 33; no. 3; p. 109
• Main Authors: Mirzaev, Karin B, Rytkin, Eric, Ryzhikova, Kristina A, Grishina, Elena A, Sozaeva, Zhannet A, Fedorinov, Denis S, Konova, Olga D, Giliarov, Michael Iu, Belyakova, Galina A, Andreev, Denis A, Sychev, Dmitriy A
• Format: Journal Article
• Language: English
• Published: Germany 25.09.2018
• Subjects: Acute Coronary Syndrome - blood; Acute Coronary Syndrome - drug therapy; Acute Coronary Syndrome - genetics; ATP Binding Cassette Transporter, Subfamily B - blood; ATP Binding Cassette Transporter, Subfamily B - genetics; Blood Platelets - drug effects; Blood Platelets - metabolism; Clopidogrel - chemistry; Clopidogrel - metabolism; Clopidogrel - pharmacokinetics; Cytochrome P-450 CYP2C19 - blood; Cytochrome P-450 CYP2C19 - genetics; Cytochrome P-450 CYP3A - blood; Cytochrome P-450 CYP3A - genetics; Cytochrome P450 Family 4 - blood; Cytochrome P450 Family 4 - genetics; Dose-Response Relationship, Drug; Female; Genotype; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors - administration & dosage; Platelet Aggregation Inhibitors - pharmacology; Polymorphism, Genetic - genetics; clopidogrel; percutaneous coronary intervention; acute coronary syndrome; polymorphism; cytochrome P450; pharmacogenetics
• ISSN: 2363-8915