Supramolecular cyclodextrin-based metal-organic framework as efficient carriers for anti-inflammatory drugs

• Published in: European journal of pharmaceutics and biopharmaceutics
• Main Authors: Abuçafy, Marina P, Caetano, Bruno L, Chiari-Andréo, Bruna G, Fonseca-Santos, Bruno, do Santos, Aline M, Chorilli, Marlus, Chiavacci, Leila A
• Format: Journal Article
• Language: English
• Published: Netherlands 08.02.2018
• Subjects: anti-inflammatory in vivo assay; γ-cyclodextrin, drug adsorption; drug delivery; metal-organic framework

Drug delivery systems have been used to reduce adverse effects and improve the efficacy of therapies. Drug carriers have been developed over the years, but they have limitations. γ-cyclodextrin-based metal-organic frameworks (γ-CD-MOF) have significant advantages due to their biocompatibility and en...