Scintigraphic imaging of Staphylococcus aureus infection using 99m Tc radiolabeled aptamers

• Published in: Applied radiation and isotopes Vol. 128; p. 22
• Main Authors: Santos, Sara Roberta Dos, de Sousa Lacerda, Camila Maria, Ferreira, Iêda Mendes, de Barros, André Luís Branco, Fernandes, Simone Odília, Cardoso, Valbert Nascimento, de Andrade, Antero Silva Ribeiro
• Format: Journal Article
• Language: English
• Published: England 01.10.2017
• Subjects: Animals; Aptamers, Nucleotide - administration & dosage; Aptamers, Nucleotide - metabolism; Aptamers, Nucleotide - pharmacokinetics; Blood Proteins - metabolism; Mice; Organotechnetium Compounds - administration & dosage; Organotechnetium Compounds - pharmacokinetics; Radionuclide Imaging - methods; Radiopharmaceuticals - administration & dosage; Radiopharmaceuticals - pharmacokinetics; Staphylococcal Infections - diagnostic imaging; Staphylococcal Infections - microbiology; Staphylococcus aureus - isolation & purification; Tissue Distribution; Bacterial infection; Radiopharmaceutical; Aptamer; Diagnosis; Technetium-99m

Staphylococcus aureus is a specie of great medical importance associated with many infections as bacteremia and infective endocarditis as well as osteoarticular, skin and soft tissue, pleuropulmonary, and device related infections. Early identification of infectious foci is crucial for successful tr...