Cytokine Signatures Discriminate Highly Frequent Acute Hepatitis A Virus and Hepatitis E Virus Co-Infections from Mono-Infections in Mexican Pediatric Patients

The frequency of HAV and HEV infections and their cytokine profiles were analyzed in Mexican pediatric patients with acute hepatitis. A high frequency of co-infections was found. Significant overexpression of IL-4, IL-12, IL-13 and IFN-gamma during HAV mono-infections and limited secretion of cytoki...

Full description

Saved in:
Bibliographic Details
Published inThe Pediatric infectious disease journal
Main Authors Realpe-Quintero, Mauricio, Copado-Villagrana, Edgar Daniel, Trujillo-Ochoa, Jorge Luis, Alvarez, Angel Hilario, Panduro, Arturo, Fierro, Nora Alma
Format Journal Article
LanguageEnglish
Published United States 26.01.2017
Online AccessGet more information

Cover

More Information
Summary:The frequency of HAV and HEV infections and their cytokine profiles were analyzed in Mexican pediatric patients with acute hepatitis. A high frequency of co-infections was found. Significant overexpression of IL-4, IL-12, IL-13 and IFN-gamma during HAV mono-infections and limited secretion of cytokines in HEV infections were observed.
ISSN:1532-0987