Non-umbilical Cutaneous Metastasis of Pancreatic Adenocarcinoma as the First Clinical Manifestation: A Case Report

Non-umbilical cutaneous metastases from pancreatic adenocarcinomas are extremely rare. Only a few cases have been reported in the literature. An 83-year-old Korean woman, with no previous medical history, presented with a painful nodule on her scalp. Histologic examination of the nodule revealed a m...

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Published inThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Vol. 68; no. 4; p. 221
Main Authors Moon, Ji In, Park, Ji Young, Jeon, Tae Joo, Choi, Jung Min, Shin, Won Chang, Sung, June Min, Kim, Young Moon, Kim, Hyun Jung
Format Journal Article
LanguageEnglish
Published Korea (South) 25.10.2016
Subjects
Abdomen - diagnostic imaging
Adenocarcinoma - diagnosis
Adenocarcinoma - pathology
Aged, 80 and over
Female
Humans
Immunohistochemistry
Keratin-19 - metabolism
Keratin-7 - metabolism
Neoplasm Metastasis
Pancreatic Neoplasms - diagnosis
Pancreatic Neoplasms - pathology
Tomography, X-Ray Computed
Immunohistochemistry
Neoplasm metastasis
Cutaneous
Pancreatic neoplasms
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Summary:Non-umbilical cutaneous metastases from pancreatic adenocarcinomas are extremely rare. Only a few cases have been reported in the literature. An 83-year-old Korean woman, with no previous medical history, presented with a painful nodule on her scalp. Histologic examination of the nodule revealed a metastatic adenocarcinoma, and immunohistochemical staining was positive for cytokeratin (CK) 7 and CK 19. These findings were consistent with a metastatic carcinoma of pancreatic origin. An abdominal computed tomography scan identified a mass on the pancreatic head and multiple enlarged lymph nodes. Pathological examination of an endoscopic ultrasound-guided fine needle biopsy of the pancreatic mass determined that it was a poorly differentiated carcinoma. The patient refused any treatment owing to her old age and short life expectancy. Four months later, the disease progressed rapidly, and the patient died.
ISSN:2233-6869