Pseudomyxoma Peritonei in a Patient with History of Breast Cancer

Pseudomyxoma peritonei is a very rare condition, and even rarer in patients with history of cancer. A 70-year old woman with a history of breast cancer was admitted with abdominal pain and distention. Abdominal computed tomography revealed ascites collection, diffuse engorgement and infiltration of...

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Published inThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Vol. 67; no. 3; p. 153
Main Authors Jung, Tae Seob, Hong, Jung Un, Park, Shin Hee, Lee, Hee Jeong, Min, In Sun, Lee, Ju Young, Seock, Chang Hyeon
Format Journal Article
LanguageEnglish
Published Korea (South) 01.03.2016
Subjects
Abdomen - diagnostic imaging
Aged
Antimetabolites, Antineoplastic - therapeutic use
Ascites
Breast Neoplasms - pathology
Colonoscopy
Female
Fluorouracil - therapeutic use
Humans
Laparoscopy
Peritoneal Neoplasms - diagnosis
Peritoneal Neoplasms - drug therapy
Peritoneal Neoplasms - pathology
Peritoneum - pathology
Pseudomyxoma Peritonei - diagnosis
Pseudomyxoma Peritonei - drug therapy
Pseudomyxoma Peritonei - pathology
Tomography, X-Ray Computed
Adenocarcinoma, mucinous
Appendiceal neoplasms
Pseudomyxoma peritonei
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Summary:Pseudomyxoma peritonei is a very rare condition, and even rarer in patients with history of cancer. A 70-year old woman with a history of breast cancer was admitted with abdominal pain and distention. Abdominal computed tomography revealed ascites collection, diffuse engorgement and infiltration of the mesenteric vessel, suggesting peritonitis or peritoneal carcinomatosis. Diagnostic paracentesis was attempted several times, but a sufficient specimen could not be collected due to the thick and gelatinous nature of the ascites. Therefore, the patient underwent diagnostic laparoscopy for tissue biopsy of the peritoneum, which indicated pseudomyxoma peritonei. However, the origin of the pseudomyxoma peritonei could not be identified intraoperatively due to adhesions and large amount of mucoceles. Systemic chemotherapy was performed using Fluorouracil, producing some symptomatic relief. After discharge, abdominal pain and distention gradually worsened, so at 18 months after initial diagnosis the patient received palliative surgery based on massive mucinous ascites and palpable mass at the omentum. The patient expired after surgery due to massive bleeding.
ISSN:2233-6869