Analysis of Phenotypic Manifestation of peanut Gene Expression Suppression by RNAi in Drosophila Oogenesis

The peanut gene functions in Drosophila melanogaster oogenesis were studied. It was demonstrated that the suppression of peanut expression by RNA interference in the ovary follicular cells results in the violation of oocyte polarization, anomalous cytokinesis in the chorion cells, and violation of t...

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Bibliographic Details
Published inGenetika Vol. 51; no. 9; p. 991
Main Authors Akhmetova, K A, Dorogova, C N, Chesnokov, I N, Fedorova, S A
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.09.2015
Subjects
Animals
Drosophila melanogaster
Drosophila Proteins - biosynthesis
Drosophila Proteins - genetics
Female
Gene Expression Regulation - physiology
Microfilament Proteins - biosynthesis
Microfilament Proteins - genetics
Oogenesis - physiology
Ovary - metabolism
RNA Interference
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Summary:The peanut gene functions in Drosophila melanogaster oogenesis were studied. It was demonstrated that the suppression of peanut expression by RNA interference in the ovary follicular cells results in the violation of oocyte polarization, anomalous cytokinesis in the chorion cells, and violation of the chromatin condensation in follicular cells. No oogenesis violations were observed in females with decreased peanut gene expression or an absence of the Pnut protein in the ovary generative cells. However, embryos produced by such females had a decreased survival rate caused by two death peaks.
ISSN:0016-6758