FeNH 4 (SO 4 ) 2 ·12H 2 O (alum)-catalyzed preparation of 1,4-dihydropyridines: improved conditions for the Hantzsch reaction

FeNH (SO ) ·12H O (alum) efficiently catalyzes the one-pot three-component reaction of dimedone, aldehydes, and 3-aminocrotonate to afford 1,4-dihydropyridines. The work-up is easy, and the products are obtained in good to excellent yields and high purity.

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Bibliographic Details
Published inMonatshefte für Chemie Vol. 143; no. 6; p. 931
Main Authors Mohammadi, Ali A, Hadadzahmatkesh, Armin, Asghariganjeh, Mohammad R
Format Journal Article
LanguageEnglish
Published Austria 2012
Subjects
Multi-component reactions
FeNH4(SO4)2·12H2O
Hantzsch reaction
1,4-Dihydropyridines
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Summary:FeNH (SO ) ·12H O (alum) efficiently catalyzes the one-pot three-component reaction of dimedone, aldehydes, and 3-aminocrotonate to afford 1,4-dihydropyridines. The work-up is easy, and the products are obtained in good to excellent yields and high purity.
ISSN:0026-9247
1434-4475