Molecular components of JAK/STAT signaling pathway and its connection with transcription machinery

JAK/STAT is one of the conservative signaling pathways in higher eukaryotes which plays a critical role in different ontogenesis processes. This article gives a review of the pathway structure at the molecular level, mainly in a model organism Drosophila. There are data about relationship of the sig...

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Bibliographic Details
Published inMolekuliarnaia biologiia Vol. 47; no. 3; p. 388
Main Authors Shaposhnikov, A V, Komar'kov, I F, Lebedeva, L A, Shidlovskiĭ, Iu V
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.05.2013
Subjects
Animals
Drosophila melanogaster
Drosophila Proteins - genetics
Drosophila Proteins - metabolism
Humans
Janus Kinases - genetics
Janus Kinases - metabolism
Signal Transduction - physiology
STAT Transcription Factors - genetics
STAT Transcription Factors - metabolism
Transcription Factors - genetics
Transcription Factors - metabolism
Transcription, Genetic - physiology
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Summary:JAK/STAT is one of the conservative signaling pathways in higher eukaryotes which plays a critical role in different ontogenesis processes. This article gives a review of the pathway structure at the molecular level, mainly in a model organism Drosophila. There are data about relationship of the signaling pathway and transcription machinery of higher eukaryotes.
ISSN:0026-8984