The effect of potential-dependent potassium uptake on membrane potential in rat brain mitochondria

• Published in: Ukrains'kyi biokhimichnyi zhurnal (1999 ) Vol. 85; no. 1; p. 33
• Main Authors: Akopova, O V, Nosar', V I, Kolchinskaia, L I, Man'kovskaia, I N, Malysheva, M K, Sagach, V F
• Format: Journal Article
• Language: Russian
• Published: Ukraine 01.01.2013
• Subjects: Adenosine Triphosphate - metabolism; Animals; Brain - drug effects; Brain - metabolism; Culture Media; Decanoic Acids - pharmacology; Glyburide - pharmacology; Hydroxy Acids - pharmacology; Ion Transport - drug effects; Kinetics; Membrane Potential, Mitochondrial - drug effects; Mitochondria - drug effects; Mitochondria - metabolism; Oxidative Phosphorylation - drug effects; Potassium - metabolism; Potassium - pharmacology; Potassium Channel Blockers - pharmacology; Potassium Channels - metabolism; Rats; Rats, Wistar

The effect of potential-dependent potassium uptake on the transmembrane potential difference (DeltaPsi(m)) in rat brain mitochondria has been studied. It was shown that in potassium concentration range of 0-120 mM the potential-dependent K(+)-uptake into matrix leads to the increase in respiration r...