Biomarkers in lupus nephritis

Systemic lupus erythematosus is a polysystemic autoimmune disease. One of the most common and serious complication is lupus nephritis. Notification of these complications before organic disorder, prediction of flares, starting aggressive therapy as early as possible, and the follow-up of successful...

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Bibliographic Details
Published inOrvosi hetilap Vol. 151; no. 29; p. 1171
Main Authors Brúgós, Boglárka, Zeher, Margit
Format Journal Article
LanguageHungarian
Published Hungary 18.07.2010
Subjects
Autoantibodies - blood
Biomarkers, Tumor - blood
Biomarkers, Tumor - urine
Chemokines - blood
Humans
Lupus Nephritis - complications
Lupus Nephritis - immunology
Lupus Nephritis - metabolism
Proteinuria - etiology
Proteinuria - metabolism
Proteome - metabolism
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Summary:Systemic lupus erythematosus is a polysystemic autoimmune disease. One of the most common and serious complication is lupus nephritis. Notification of these complications before organic disorder, prediction of flares, starting aggressive therapy as early as possible, and the follow-up of successful treatment would be desirable. There is an intensive need for identifying the best biomarker for monitoring flare activity. The goal of this review is to present not only the most frequently ordered serologic tests, but the latest, partly experimental biomarkers reflecting flares, which are not used in clinical practice. Biomarkers used specifically in lupus nephritis are also described.
ISSN:0030-6002