Quantification of antineural antibodies in autoimmune neurological disorders
More than 50 different neurological pathologies have a confirmed or suspected autoimmune etiology affecting an estimated number of 75 million people worldwide. Autoantibodies are a useful diagnostic marker for most autoimmune diseases even though their pathological role is not evident, and several t...
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| Published in | Expert review of clinical immunology Vol. 3; no. 6; p. 949 |
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| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
England
01.11.2007
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| Online Access | Get more information |
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| Summary: | More than 50 different neurological pathologies have a confirmed or suspected autoimmune etiology affecting an estimated number of 75 million people worldwide. Autoantibodies are a useful diagnostic marker for most autoimmune diseases even though their pathological role is not evident, and several tests for their detection are commercially available. However, for autoimmune diseases involving the nervous system, lack of clear information on the identity of antineural antibody targets and the presence of many rare diseases have hampered the development of specific diagnostic assays. This review focuses on the actual knowledge on confirmed and suspected autoimmune diseases that target the CNS and the diagnostic relevance of corresponding antineural autoantibodies. |
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| ISSN: | 1744-8409 |