Obtaining group-specific fluorescent immunoglobulin for diagnosis of adenovirus infection

The authors present the results of a comparative study of several schemes of rabbit immunization with mixtures consisting of 4 and 7 (mixture No. 1) nad 2, 4, and 7 (mixture No. 2) adenovirus types for the purpose of obtaining group-specific fluorescent immunoglobulins. Since a direct correlative de...

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Bibliographic Details
Published inŽurnal mikrobiologii, ėpidemiologii i immunobiologii no. 6; p. 67
Main Authors Matskevich, A L, Lanskaia, T I, Erilova, S P, Blizniuk, V V, Stanislavskaia, V K
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.06.1977
Subjects
Adenoviridae Infections - diagnosis
Adenovirus Infections, Human - diagnosis
Adenoviruses, Human - immunology
Animals
Antibodies, Bacterial
Antibody Specificity
Fluorescent Antibody Technique
Humans
Immunoglobulins
Rabbits - immunology
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Summary:The authors present the results of a comparative study of several schemes of rabbit immunization with mixtures consisting of 4 and 7 (mixture No. 1) nad 2, 4, and 7 (mixture No. 2) adenovirus types for the purpose of obtaining group-specific fluorescent immunoglobulins. Since a direct correlative dependence of the activity of fluorescent immunoglobulins on the antibody level to the adenoviruses of homologous type was revealed in the immune sera a combined scheme of mixture No. 2 administration was elaborated for the immunization of animals.
ISSN:0372-9311