Inhibition of cardiolipin binding antibodies from synovial fluids of patients with arthritis by endotoxin

In the presented study was prooven that aCl antibodies cross-reacting with LPS (endotoxin) from arthritic synovial fluids are part of the aPL antibodies pool and correlated with presence in joints bacterial cell wall components like LPS-showing endotoxin presence in synovial fluids and they may be u...

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Bibliographic Details
Published inPolskie archiwum medycyny wewne̦trznej Vol. 115; no. 5; p. 447
Main Authors Zabek, Jakub, Noworyta, Jacek, Brasse-Rumin, Maria, Rell-Bakalarska, Maria
Format Journal Article
LanguagePolish
Published Poland 01.05.2006
Subjects
Antibodies, Anticardiolipin - immunology
Antibodies, Bacterial - analysis
Antigens, Bacterial - analysis
Arthritis - diagnosis
Arthritis - immunology
Arthritis, Rheumatoid - diagnosis
Biomarkers - metabolism
Cross Reactions
Diagnosis, Differential
Humans
Immunologic Tests
Lipopolysaccharides - immunology
Lipopolysaccharides - metabolism
Osteoarthritis - diagnosis
Osteoarthritis - immunology
Synovial Fluid - immunology
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Summary:In the presented study was prooven that aCl antibodies cross-reacting with LPS (endotoxin) from arthritic synovial fluids are part of the aPL antibodies pool and correlated with presence in joints bacterial cell wall components like LPS-showing endotoxin presence in synovial fluids and they may be usefull in differential diagnosis of the different kind of arthritis and also in explanation of their aetiology at all--especially in cases of early, undifferentiated arthritis.
ISSN:1897-9483