Incidental diagnosis of lymph node tuberculosis in an 111-indium-octreotide scintigraphy during a study of acromegaly

A patient with clinical suspicion of acromegaly and no radiologic visualization of pituitary adenoma is presented. (111)In-DTPAOC scintigraphy was performed in order to localize an ectopic foci of GH production. Scintigraphy showed uptake in right paratracheal and hiliar lymph nodes that seemed resi...

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Bibliographic Details
Published inRevista española de medicina nuclear Vol. 25; no. 3; p. 193
Main Authors Tabuenca Dopico, O, Gutiérrez Mendiguchía, C, Rego Iraeta, A
Format Journal Article
LanguageSpanish
Published Spain 01.05.2006
Subjects
Acromegaly - complications
Acromegaly - diagnostic imaging
Adenoma - diagnosis
Adenoma - secretion
Aged
False Negative Reactions
Humans
Incidental Findings
Indium Radioisotopes - pharmacokinetics
Insulin-Like Growth Factor I - analysis
Male
Octreotide - analogs & derivatives
Octreotide - pharmacokinetics
Pentetic Acid - analogs & derivatives
Pentetic Acid - pharmacokinetics
Pituitary Neoplasms - diagnosis
Pituitary Neoplasms - secretion
Radionuclide Imaging
Radiopharmaceuticals - pharmacokinetics
Tuberculosis, Lymph Node - complications
Tuberculosis, Lymph Node - diagnostic imaging
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Summary:A patient with clinical suspicion of acromegaly and no radiologic visualization of pituitary adenoma is presented. (111)In-DTPAOC scintigraphy was performed in order to localize an ectopic foci of GH production. Scintigraphy showed uptake in right paratracheal and hiliar lymph nodes that seemed residual in CT. Biopsy through mediastinoscopy showed tuberculous granulomas. After treatment, scintigraphy normalized. This case illustrate that (111)In-DTPAOC can be positive not only in tumoral but in benign pathology and, in specific cases, it can be a marker of inflammatory activity and useful for treatment monitoring.
ISSN:0212-6982