Coronary plaque instability in severe acute respiratory syndrome

In his second week of severe acute respiratory syndrome (SARS) illness, a patient developed an unusually complicated course of acute coronary syndrome. One day after initial stabilization of a non-ST-elevated anterior myocardial infarction (MI), he sustained an ST-elevated anterior MI. Eight hours a...

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Bibliographic Details
Published inInternational journal of cardiology Vol. 99; no. 3; p. 471
Main Authors Tsui, Kin-Lam, Leung, Tat-Chi, Yam, Loretta Yin-Chun, So, Loletta Kit-Ying, Poon, Edwin, Lung, Kwok-Cheung, Li, Shu-Kin
Format Journal Article
LanguageEnglish
Published Netherlands 30.03.2005
Subjects
Aged
Coronary Angiography
Fatal Outcome
Humans
Male
Myocardial Infarction - diagnostic imaging
Myocardial Infarction - etiology
Severe Acute Respiratory Syndrome - complications
Syndrome
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Summary:In his second week of severe acute respiratory syndrome (SARS) illness, a patient developed an unusually complicated course of acute coronary syndrome. One day after initial stabilization of a non-ST-elevated anterior myocardial infarction (MI), he sustained an ST-elevated anterior MI. Eight hours after emergency coronary intervention to the culprit lesion, he developed another ST-elevated MI in the inferior territory. Acute inflammation and cytokine storm in the immunopathological phase of SARS may play a role in coronary plaque instability. Physicians should be alert to this potentially fatal complication and adopt appropriate vigilant and aggressive management strategies.
ISSN:0167-5273