Effect of baoyuantang on erythroid progenitor and clinical observation in chronic renal failure patients

The erythroid colony formating ability and the therapeutic efficacy were investigated in patients with chronic renal failure (CRF) before and after treatment with baoyuantang. The results showed that the number of CFU-E, BFU-E of bone marrow was found lower in CRF patients than that in normal contro...

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Bibliographic Details
Published inZhongguo Zhong xi yi jie he za zhi Vol. 12; no. 8; p. 461
Main Authors Jin, Y P, Song, Q C, Wu, H
Format Journal Article
LanguageChinese
Published China 01.08.1992
Subjects
Adult
Bone Marrow - pathology
Colony-Forming Units Assay
Creatinine - blood
Drugs, Chinese Herbal - pharmacology
Drugs, Chinese Herbal - therapeutic use
Erythroid Precursor Cells - drug effects
Female
Hemoglobins - metabolism
Humans
Kidney Failure, Chronic - blood
Kidney Failure, Chronic - drug therapy
Male
Middle Aged
Panax
Plants, Medicinal
Yang Deficiency - drug therapy
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Summary:The erythroid colony formating ability and the therapeutic efficacy were investigated in patients with chronic renal failure (CRF) before and after treatment with baoyuantang. The results showed that the number of CFU-E, BFU-E of bone marrow was found lower in CRF patients than that in normal controls, and there was inhibitory action in the CRF serum on the number of CFU-E, BFU-E of normal human bone marrow. After treatment with baoyuantang, the amount of Hb was increased and creatinine decreased in CRF patients, and its effective rate reached 83.3%. The above-mentioned inhibitory action in CRF serum was also reduced post-treatment. The results indicated that baoyuantang could increase the ability for proliferation and differentiation of erythroid progenitor and adjust anemia in CRF patient.
ISSN:1003-5370