Refractory effect and alloimmunization after transfusion of thrombocytes
The authors discuss possible ways for prevention of alloimmunization with HLA-antigen in acute leukemia patients after platelet transfusions. Prevention or delay of HLA-alloimmunization is possible when platelets of single random donor are used instead of pooled random donor platelets for transfusio...
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Published in | Gematologiia i transfuziologiia Vol. 37; no. 2; p. 16 |
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Main Authors | , |
Format | Journal Article |
Language | Russian |
Published |
Russia (Federation)
01.02.1992
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Subjects | |
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Abstract | The authors discuss possible ways for prevention of alloimmunization with HLA-antigen in acute leukemia patients after platelet transfusions. Prevention or delay of HLA-alloimmunization is possible when platelets of single random donor are used instead of pooled random donor platelets for transfusions. The effect of leucocyte removal from platelet concentrates and ultraviolet irradiation of platelet concentrates under conditions of blood bank on alloimmunization and refractoriness incidence has been considered. |
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AbstractList | The authors discuss possible ways for prevention of alloimmunization with HLA-antigen in acute leukemia patients after platelet transfusions. Prevention or delay of HLA-alloimmunization is possible when platelets of single random donor are used instead of pooled random donor platelets for transfusions. The effect of leucocyte removal from platelet concentrates and ultraviolet irradiation of platelet concentrates under conditions of blood bank on alloimmunization and refractoriness incidence has been considered. |
Author | Volkova, R I Agranenko, V A |
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Snippet | The authors discuss possible ways for prevention of alloimmunization with HLA-antigen in acute leukemia patients after platelet transfusions. Prevention or... |
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SubjectTerms | Anaphylaxis - etiology Anaphylaxis - immunology Anaphylaxis - prevention & control Blood Donors Blood Platelets - immunology Hemofiltration - methods Hemorrhage - immunology Hemorrhage - therapy HLA Antigens - immunology Humans Leukemia - immunology Leukemia - therapy Leukocyte Count Leukocytes - immunology Platelet Count Platelet Transfusion Transfusion Reaction |
Title | Refractory effect and alloimmunization after transfusion of thrombocytes |
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