Clearing the confusion

In patients who do not achieve a response or are intolerant to one CEI, it is reasonable to switch to another CEI. Generally, no washout period is required. The second CEI can be initiated at the minimal therapeutic dose the day after the initial CEI is stopped and then titrated up to the therapeuti...

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Bibliographic Details
Published inPharmacy Practice Vol. 22; no. 2; p. 40
Main Author Kwan, Debora
Format Trade Publication Article
LanguageEnglish
Published Mississauga EnsembleIQ 01.02.2006
Subjects
Alzheimer's disease
Caregivers
Cognition & reasoning
Delirium
Disease management
Enzymes
Genotype & phenotype
Medical diagnosis
Medical treatment
Neurodegeneration
Patients
Pharmacists
Quality of life
Risk factors
Canada
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Summary:In patients who do not achieve a response or are intolerant to one CEI, it is reasonable to switch to another CEI. Generally, no washout period is required. The second CEI can be initiated at the minimal therapeutic dose the day after the initial CEI is stopped and then titrated up to the therapeutic dose.24 Starting the new CEI at subtherapeutic doses is not necessary and is undesirable for two reasons.
ISSN:0829-2809