Guillain-Barré Syndrome During Ongoing Zika Virus Transmission - Puerto Rico, January 1-July 31, 2016

Guillain-Barr... syndrome (GBS) is an uncommon autoimmune disorder characterized by varying degrees of weakness, sensory abnormalities, and autonomic dysfunction due to peripheral nerve or nerve root damage. Countries affected by Zika virus have reported increased numbers of cases of GBS. After iden...

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Published inMMWR. Morbidity and Mortality Weekly Report Vol. 65; no. 34; p. 910
Main Authors Dirlikov, Emilio, Major, Chelsea G, Mayshack, Marrielle, Medina, Nicole, Matos, Desiree, Ryff, Kyle R, Torres-Aponte, Jomil, Alkis, Rebecca, Munoz-Jordan, Jorge, Colon-Sanchez, Candimar, Salinas, Jorge L, Pastula, Daniel M, Garcia, Myriam, Segarra, Marangely Olivero, Malave, Graciela, Thomas, Dana L, Rodríguez-Vega, Gloria M, Luciano, Carlos A, Sejvar, James, Sharp, Tyler M, Rivera-Garcia, Brenda
Format Report
LanguageEnglish
Published Atlanta U.S. Center for Disease Control 02.09.2016
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Summary:Guillain-Barr... syndrome (GBS) is an uncommon autoimmune disorder characterized by varying degrees of weakness, sensory abnormalities, and autonomic dysfunction due to peripheral nerve or nerve root damage. Countries affected by Zika virus have reported increased numbers of cases of GBS. After identification of local transmission of Zika virus in Puerto Rico in December 2015, the Puerto Rico Department of Health implemented the GBS Passive Surveillance System in February 2016. Among 56 patients with suspected GBS who had onset of neurologic symptoms during January 1-July 31, 2016, evidence of Zika or other flavivirus infection was present in 34 (61%), including 10 (18%) with confirmed Zika virus infection. The median age of the 34 patients was 55 years, and 59% were female. Thirty (88%) patients reported an acute illness before developing neurologic symptoms, with median time to onset of neurologic symptoms of 5 days. One patient died from septic shock after treatment for GBS.
ISSN:0149-2195
1545-861X