GC-MS and UHPLC-MS-MS Analysis of Organic Contaminants and Hormones in Whale Earwax Using Selective Pressurized Liquid Extraction

Here we highlight some of the opportunities associated with combining advanced sample preparation techniques with stateof-the-art chemical analysis techniques. This article considers the unique combination of selective pressurized liquid extraction (SPLE) with gas chromatography (GC) coupled with ma...

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Bibliographic Details
Published inLC GC North America p. 40
Main Authors Usenko, Sascha, Winfield, Zach C, Thumble, Stephen J, Lysiak, Nadine
Format Trade Publication Article
LanguageEnglish
Published Monmouth Junction MultiMedia Healthcare Inc 01.10.2015
Subjects
Adsorbents
Analytical chemistry
Chemicals
Chromatography
Efficiency
Experiments
Hormones
Immunoassay
Mass spectrometry
Methods
Organic contaminants
Scientific imaging
Sodium
Solvents
Testosterone
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Summary:Here we highlight some of the opportunities associated with combining advanced sample preparation techniques with stateof-the-art chemical analysis techniques. This article considers the unique combination of selective pressurized liquid extraction (SPLE) with gas chromatography (GC) coupled with mass spectrometry (MS) and ultrahigh-pressure liquid chromatography coupled with tandem MS (UHPLC-MS-MS). We use this powerful combination to develop a novel analytical technique capable of measuring hormones and organic contaminants in whale earwax plugs. We explore the analytical challenges with such combinations and the advantages of focusing both on sample preparation as well as chemical analysis.
ISSN:1527-5949
1939-1889