UPDATE: Dementia: part 1

At post-mortem, DLB is characterised by the presence of [Lewy] bodies in the cerebral cortex and substantia nigra. Lewy bodies are also found in post-mortem brains of people with Parkinson's disease, Pick's disease and Huntington's chorea. Sufferers are extremely sensitive to extrapyr...

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Bibliographic Details
Published inChemist & Druggist p. 12
Main Author Feetam, Celia
Format Trade Publication Article
LanguageEnglish
Published London CMP Information Ltd 17.11.2012
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Summary:At post-mortem, DLB is characterised by the presence of [Lewy] bodies in the cerebral cortex and substantia nigra. Lewy bodies are also found in post-mortem brains of people with Parkinson's disease, Pick's disease and Huntington's chorea. Sufferers are extremely sensitive to extrapyramidal side effects of antipsychotics, which - including some of the atypicals - are associated with a two to threefold increase in mortality in DLB patients.
ISSN:0009-3033