Rapid and homogeneous reperfusion as a risk factor for postreperfusion syndrome during orthotopic liver transplantation

• Published in: Revista brasileira de anestesiologia Vol. 60; no. 2; pp. 88 - 92
• Main Authors: Cordoví de Armas, Lucas, Jiménez Paneque, Rosa E, Gala López, Boris, Rápalo Romero, Edin Ismael, Añuez Castillo, Ydriss, Vallongo Menéndez, Marina Beatriz
• Format: Journal Article
• Language: English; Portuguese; Spanish
• Published: 01.03.2010
• ISSN: 1806-907X

BACKGROUND AND OBJECTIVESThe revascularization of the graft remains as a crucial instant of the orthotopic liver transplantation (OLT) surgical procedure. About a third of the recipients suffer the postreperfusion syndrome (PRS), a combination of hypothermia, metabolic disorders and cardiovascular instability potentially leading to cardiac arrest. The objective of this study was to evaluate the speed-quality (SQR) of the graft;s reperfusion as an independent predictor of PRS.METHODSAll eligible patients receiving an OLT in our institution from 1987 to march 2009 were included. The adjusted OR for SQR-PRS association was obtained by means of logistic regression modeling including eight potential confounders.RESULTSThe proportion of recipients suffering PRS was highest when the SQR was identified as good (75.8%) compared to those with middle or poor SQR; the relative risk comparing good SQR with poor SQR was 12.9 (CI 95%: 2.1-528.8). The adjusted OR was 132.9 (95% CI: 10.5-1688.6) when comparing good with bad SQR and 90.9 (95% CI: 13.8-645.2) when comparing good with intermediate SQR.CONCLUSIONSAccording to our results, SQR can be considered an unambiguous predictor of PRS.