Life-time adversities, reported thirteen years after a suicide attempt: relationship to recovery, 5ht TLPR genotype, and past and present morbidity

In this study, we investigated how adversities related to past and present morbidity, and genotype. Forty-two, suicide attempters and 22 matched control patients were followed-up after 13 years. Life-time adversities were explored in an interview, and the patients were reassessed psychiatrically. Th...

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Published inArchives of suicide research Vol. 13; no. 3; pp. 214 - 229
Main Authors Vang, Fredrik, Lindstrom, Mats, Sunnqvist, Charlotta, Bah-Rosman, Jessica, Johanson, Aki, Traskman-Bendz, Lil
Format Journal Article
LanguageEnglish
Published 01.07.2009
Subjects
Case studies
Depression
Genes
Interviews
Mental health
Morbidity
Social psychology
Suicide
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Summary:In this study, we investigated how adversities related to past and present morbidity, and genotype. Forty-two, suicide attempters and 22 matched control patients were followed-up after 13 years. Life-time adversities were explored in an interview, and the patients were reassessed psychiatrically. The serotonin-transporter-linked promotor region (5-HTTLPR) was typed. More adversities were reported by suicide attempters than controls, and by still-ill than recovered suicide attempters. Adversities reported at follow-up were related to psychiatric morbidity at follow-up, but not to morbidity 13 years earlier. The 5-HTTLPR, genotype was associated with reported adversities, but not chances of recovery. Adversities potentially affected chronic morbidity. 5-HTTLPR genotype did not affect long-term recovery. Reprinted by permission of Taylor and Francis Ltd.
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ISSN:1381-1118
DOI:10.1080/13811110903044328