Heart Failure With Reduced Ejection Fraction in a Patient With Erdheim-Chester Disease on Dabrafenib

A 54-year-old woman with a diagnosis of Erdheim-Chester disease under therapy with dabrafenib presents with clinical signs of heart failure. After discontinuing the offending medication and initiating guideline-directed medical therapy for heart failure with reduced ejection fraction, the clinical p...

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Published inJACC. Case reports Vol. 29; no. 12; p. 102374
Main Authors Saenz-Ancira, Santiago, Higuera-Ornelas, Javier, Bernades-Souza, Breno, Severdija, Ryan, Santa Ana-Bayona, Maria Jose, Silvana Salazar, Maria, Vazquez, Moises A, Luna-Alvarez, Jose Antonio
Format Report
LanguageEnglish
Published 19.06.2024
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Summary:A 54-year-old woman with a diagnosis of Erdheim-Chester disease under therapy with dabrafenib presents with clinical signs of heart failure. After discontinuing the offending medication and initiating guideline-directed medical therapy for heart failure with reduced ejection fraction, the clinical picture improved.
Bibliography:ObjectType-Case Study-2
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SourceType-Reports-1
ObjectType-Report-1
ISSN:2666-0849
DOI:10.1016/j.jaccas.2024.102374