Disseminated Cryptococcal Infection in Treatment-Naive Patients With Chronic Lymphocytic Leukemia (CLL)

This case report highlights a rare occurrence of disseminated cryptococcal infection in an elderly male with untreated chronic lymphocytic leukemia (CLL). Despite lacking prior treatment for CLL, the patient presented with respiratory symptoms and was found to have Cryptococcus neoformans in blood c...

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Bibliographic Details
Published inCureus Vol. 16; no. 4; p. e59022
Main Authors Gujabidze, Kakha, Hussain, Subaha Akram, Balint, Stephanie, Saadeh, Basel, Yucelen, Sumeyra, Shiferaw, Bethel
Format Report
LanguageEnglish
Published 01.04.2024
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Summary:This case report highlights a rare occurrence of disseminated cryptococcal infection in an elderly male with untreated chronic lymphocytic leukemia (CLL). Despite lacking prior treatment for CLL, the patient presented with respiratory symptoms and was found to have Cryptococcus neoformans in blood cultures. Prompt initiation of antifungal therapy was crucial, although central nervous system involvement was absent. The case underscores the importance of considering fungal infections in CLL patients, emphasizing the immunological vulnerabilities associated with the disease. Heightened awareness and early management are essential in addressing such opportunistic infections in this patient population.
Bibliography:ObjectType-Case Study-2
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SourceType-Reports-1
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ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.59022