Isolated neurofibroma of the urinary bladder incidentally discovered during cystoscopy

• Published in: Urology case reports Vol. 54; p. 102740
• Main Authors: Warn, Michael J, Hasegawa, Jason S, Handler, Stephanie J
• Format: Report
• Language: English
• Published: 01.05.2024
• ISSN: 2214-4420; 2214-4420
• DOI: 10.1016/j.eucr.2024.102740

Isolated neurofibromas of the urinary bladder are rare benign tumors typically associated with neurofibromatosis type 1 (NF-1). Herein highlights a bladder neurofibroma incidentally discovered during cystoscopy following midurethral sling removal in a 61-year-old woman without NF-1 sequela. Despite malignancy concerns due to smoking history, histology confirmed a benign neurofibroma. These tumors differ from NF-1-associated neurofibromas in origin and presentation; they are rare, often asymptomatic, and likely stem from somatic mutations. Conservative management is preferred, with surgical intervention indicated only for obstructive masses.