Can Salmonella typhi Cause Acute Appendicitis?

• Published in: Cureus Vol. 16; no. 1; p. e53213
• Main Authors: Mithany, Reda H, Shaikh, Amarah, Scott, Catherine, Abdalla, Mazin, Graham, Matthew, Gerogiannis, Ioannis N
• Format: Report
• Language: English
• Published: 01.01.2024
• ISSN: 2168-8184; 2168-8184
• DOI: 10.7759/cureus.53213

Salmonella typhi, commonly known for causing typhoid fever, is recognized as a bacterium responsible for a wide range of gastrointestinal and systemic infections. While its systemic manifestations have been well-documented, its association with localized gastrointestinal complications, such as appendicitis, remains relatively rare and less explored. This case report presents a compelling clinical case of a 55-year-old patient who presented with symptoms of gastrointestinal distress and was diagnosed with S. typhi-induced appendicitis. The patient's history, clinical presentation, laboratory investigations, radiological findings, management, and outcomes are thoroughly discussed. The report also touches upon the broader context of appendicitis etiology and highlights the significance of prompt diagnosis and intervention in cases of Salmonella-induced appendicitis.