Immune-mediated necrotizing myopathy: Report of two cases

BACKGROUNDImmune-mediated necrotizing myopathy is a rare autoimmune myopathy characterized by muscle weakness and elevated serum creatine kinase, with unique skeletal muscle pathology and magnetic resonance imaging features. CASE SUMMARYIn this paper, two patients are reported: One was positive for...

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Published inWorld journal of clinical cases Vol. 11; no. 15; pp. 3552 - 3559
Main Authors Chen, Bi-Hong, Zhu, Xue-Min, Xie, Lei, Hu, Huai-Qiang
Format Report
LanguageEnglish
Published 26.05.2023
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Summary:BACKGROUNDImmune-mediated necrotizing myopathy is a rare autoimmune myopathy characterized by muscle weakness and elevated serum creatine kinase, with unique skeletal muscle pathology and magnetic resonance imaging features. CASE SUMMARYIn this paper, two patients are reported: One was positive for anti-signal recognition particle antibody, and the other was positive for anti-3-hydroxy-3-methylglutaryl coenzyme A reductase antibody. CONCLUSIONThe clinical characteristics and treatment of the two patients were analysed, and the literature was reviewed to improve the recognition, diagnosis, and treatment of this disease.
Bibliography:ObjectType-Case Study-2
content type line 59
SourceType-Reports-1
ObjectType-Report-1
ISSN:2307-8960
2307-8960
DOI:10.12998/wjcc.v11.i15.3552