Relationship between Blood Glucose and Lipid Levels and Intestinal Bifidobacteriumin Middle-Aged and Older Adults in Chengdu

• Published in: Sichuan da xue xue bao. Journal of Sichuan University. Yi xue ban Vol. 53; no. 2; pp. 297 - 302
• Main Authors: Wang, Ke, Cui, Jia, Lu, Qiu-Xian, Chen, Shu-Qiao, Peng, Tian-Yu, Li, Ming, Guo, Yun, Jiang, Li, He, Fang, Yu, Xiao-Hong, Wu, Xi, Liu, Xiao-Rong
• Format: Journal Article
• Language: Chinese
• Published: 01.03.2022
• ISSN: 1672-173X
• DOI: 10.12182/20220360105

ObjectiveTo explore characteristics of the species structure of the genus Bifidobacterium at different levels of blood glucose and lipid in middle-aged and older adults in Chengdu so as to provide research basis for applying bifidobacteria in the prevention and treatment of hyperglycemia and dyslipidemia.MethodsA total of 289 middle-aged and older adults of 45 and older were recruited in Chengdu between April and August 2018. They were divided into the healthy group, the dyslipidemia group, the hyperglycemia group, and the combination group (of subjects with both dyslipidemia and hyperglycemia). The levels of their fasting blood glucose (GLU), total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were examined. In addition, stool samples were collected and real-time fluorescence quantitative PCR was used for quantitative analysis of the genus Bifidobacteriumand the 8 bifidobacteria most commonly found in human intestines, the r