Therapeutic potential of silymarin as a natural iron-chelating agent in β-thalassemia intermedia

Abnormal iron accumulation in vital organs is one of the major complications of β-thalassemia intermedia (β-TI). Silymarin, a flavonolignan isolated from Silybum marianum, significantly decreases the serum ferritin levels of β-TI patients. This finding suggests silymarin as a safe and effective natu...

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Published inClinical case reports Vol. 10; no. 1; p. e05293
Main Authors Reisi, Nahid, Esmaeil, Nafiseh, Gharagozloo, Marjan, Moayedi, Behjat
Format Report
LanguageEnglish
Published 01.01.2022
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Summary:Abnormal iron accumulation in vital organs is one of the major complications of β-thalassemia intermedia (β-TI). Silymarin, a flavonolignan isolated from Silybum marianum, significantly decreases the serum ferritin levels of β-TI patients. This finding suggests silymarin as a safe and effective natural iron-chelating agent for the treatment of iron-overloaded conditions.
Bibliography:ObjectType-Case Study-2
content type line 59
SourceType-Reports-1
ObjectType-Report-1
ISSN:2050-0904
2050-0904
DOI:10.1002/ccr3.5293