Activity of chronic spontaneous urticaria in euthyroid vs hypothyroid patients

• Published in: Revista alergia Mexico (Tecamachalco, Pueblo, Mexico : 1993) Vol. 67; no. 2; pp. 112 - 118
• Main Authors: Herrera-Sánchez, Diana Andrea, Álvarez-Chávez, Fabián Eduardo, O Farrill-Romanillos, Patricia María
• Format: Journal Article
• Language: Spanish
• Published: 01.04.2020
• ISSN: 0002-5151
• DOI: 10.29262/ram.v67i2.635

BACKGROUNDChronic urticaria (CU) affects 5 % of the general population and it is associated with thyroid disease in up to 54 % of patients. There is scarce information on the activity of urticaria in patients with and without alterations in the thyroid function. OBJECTIVETo compare the activity rate of urticaria using the UAS7 (Urticaria Activity Score 7) in patients with and without hypothyroidism. METHODSA descriptive, cross-sectional, and comparative study of patients with CSU (chronic spontaneous urticaria) who were older than 18 years of age, who were classified into two groups based on their thyroid function: hypothyroid and euthyroid patients. UAS7 was applied to all of them. RESULTSWe analyzed 60 patients with CSU; 30 of them were euthyroid and 30 were hypothyroid. The female sex was predominant (76 %) and the average age was 49.1 years old. The activity in 40 % was moderate, in 25 % was severe, and it was mild in 23 %; only 12 % of them were controlled. In the group with hypothyroidism, the median TSH (Thyroid Stimulating Hormone) was of 6.8 μUI/mL. No statistically significant differences were found in matters of age, body mass index, comorbidities, or in the UAS7. CONCLUSIONSWe did not find a statistically significant difference in the Urticaria Activity Index between both groups. Identifying the influencing factors shall improve the quality of life of patients.