Prevention of Recurrent Mucinous Borderline Ovarian Tumor with Aromatase Inhibitor

BACKGROUNDAromatase inhibitors (AIs) are used for estrogen-modulated conditions. Some borderline ovarian tumors (BOT) express estrogen receptors. We present 2 cases of progression from mucinous cystadenoma to mucinous BOT (mBOT) after prior cystectomies in whom an AI was used with recurrence prevent...

Full description

Saved in:
Bibliographic Details
Published inJournal of pediatric and adolescent gynecology Vol. 33; no. 5; pp. 610 - 612
Main Authors Stambough, Kathryn C, Muscal, Jodi A, Edwards, Creighton L, Dietrich, Jennifer E
Format Report
LanguageEnglish
Published 01.10.2020
Online AccessGet full text

Cover

More Information
Summary:BACKGROUNDAromatase inhibitors (AIs) are used for estrogen-modulated conditions. Some borderline ovarian tumors (BOT) express estrogen receptors. We present 2 cases of progression from mucinous cystadenoma to mucinous BOT (mBOT) after prior cystectomies in whom an AI was used with recurrence prevention. CASESTwo patients underwent laparoscopic ovarian cystectomy for mucinous cystadenoma. Serial imaging demonstrated recurrent ovarian cysts for which both underwent fertility sparing surgery (FSS) with ovarian cystectomy for mBOT. Both patients were initiated on an AI and have been without recurrence. SUMMARY AND CONCLUSIONBOT predominantly occur in reproductive aged females. FSS with cystectomy is an option, but recurrence occurs in 12-36% of cases. The use of AI in prevention of recurrent BOT shows promise, and more studies are needed to explore this treatment.
Bibliography:ObjectType-Case Study-2
content type line 59
SourceType-Reports-1
ObjectType-Report-1
ISSN:1873-4332
DOI:10.1016/j.jpag.2020.03.011