ESAT-6 Peptide Recognition by Bovine CD8 super(+) Lymphocytes of Naturally Infected Cows in Herds from Southern Italy

The aim of this study was to define epitopes of Mycobacterium bovis from ESAT-6 (early secretory antigen of 6 kDa) recognized by CD8 super(+) T lymphocytes from cows naturally infected with Mycobacterium bovis. We found that bovine CD8 super(+) T cells recognized 10 out of 11 ESAT-6 peptides tested.

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Bibliographic Details
Published inClinical and vaccine immunology Vol. 13; no. 4; pp. 530 - 533
Main Authors Vitale, Fabrizio, Reale, Stefano, Petrotta, Enrico, Caracappa, Santo, Barera, Annalisa, La Manna, Marco Pio, Macaluso, Pasquale, Caccamo, Nadia, Dieli, Francesco, Vordermeier, Hans Martin, Sireci, Guido, Salerno, Alfredo
Format Journal Article
LanguageEnglish
Published 01.04.2006
Subjects
Mycobacterium bovis
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Summary:The aim of this study was to define epitopes of Mycobacterium bovis from ESAT-6 (early secretory antigen of 6 kDa) recognized by CD8 super(+) T lymphocytes from cows naturally infected with Mycobacterium bovis. We found that bovine CD8 super(+) T cells recognized 10 out of 11 ESAT-6 peptides tested.
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ISSN:1556-6811
1556-679X