MRI parameters of Alzheimeras disease in an Arab population of Wadi Ara, Israel
Magnetic resonance imaging (MRI) findings are reported from 15 individuals in an ArabaIsraeli community who were diagnosed with Alzheimeras disease (AD). The quantitative parameters that were used for MRI analyses included gradings (0a3) and linear measurements of different brain structures. General...
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Published in | Neuropsychiatric disease and treatment Vol. 1; no. 1; pp. 77 - 85 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
01.03.2005
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Online Access | Get full text |
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Summary: | Magnetic resonance imaging (MRI) findings are reported from 15 individuals in an ArabaIsraeli community who were diagnosed with Alzheimeras disease (AD). The quantitative parameters that were used for MRI analyses included gradings (0a3) and linear measurements of different brain structures. Generalized tissue loss was assessed by combined measurements of the ventricles (ventricular score, VS) and sulcal grading and width (SG, SW, respectively). Loss of brain tissue in specific regions of interest, eg, temporal lobes, basal ganglia, and midbrain, was evaluated by precise measurements. We observed abnormal tissue characteristics, expressed as high intensity foci in white matter on T2W sequences, as well as tissue loss, both generalized and focal. Most notable were changes involving the head of the caudate nuclei, the midbrain, and to a lesser degree, medial temporal structures. |
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Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 content type line 23 ObjectType-Feature-1 |
ISSN: | 1176-6328 1178-2021 |