Juvenile X-linked retinoschisis responsive to intravitreal corticosteroids

• Published in: American journal of ophthalmology case reports Vol. 5; pp. 48 - 51
• Main Authors: Ansari, Waseem H, Browne, Andrew W, Singh, Rishi P
• Format: Report
• Language: English
• Published: 01.04.2017
• ISSN: 2451-9936
• DOI: 10.1016/j.ajoc.2016.12.002

PURPOSETo report the case of an adult male with X-linked retinoschisis (XLRS) who presented with cystoid macular edema (CME) that responded consistently to treatment with intravitreal steroids. OBSERVATIONSA 39 year old male with unilateral presentation of CME after repair of a retinal detachment secondary to XLRS responded initially to an injection of intravitreal triamcinolone acetonide (IVTA). Central subfield thickness on OCT was reduced. Three months later, the CME recurred and he was unresponsive to topical treatment so repeat IVTA was given, and the CME once again was reduced dramatically. After the next recurrence, intravitreal dexamethasone implant treatment was initiated and successful at treating recurrences in 3 month intervals for 5 additional injections. Finally, an intravitreal fluocinolone acetonide implant was surgically placed with control of CME. CONCLUSIONS AND IMPORTANCECorticosteroids have never been reported to be effective in CME related to XLRS. Here, we document a case of a man who successfully had decrease of intraretinal fluid and schisis with treatment of intravitreal corticosteroids as demonstrated by spectral domain optical coherence tomography.