Synthesis and properties of a symmetric dimeric bisbenzimidazole, a DNA-specific ligand

• Published in: Russian journal of bioorganic chemistry Vol. 34; no. 2; pp. 261 - 263
• Main Authors: Ivanov, A A, Streltsov, SA, Prikazchikova, T A, Gottikh, M B, Zhuze, AL
• Format: Journal Article
• Language: English
• Published: 01.03.2008
• Subjects: Human immunodeficiency virus 1

Dimeric bisbenzimidazole DB(5) fluorescing in the blue spectral area ( lambda sub(em) 476 nm) within the DNA complex was synthesized. DB(5) is bound by a double-strand DNA and can differentially stain human and plant (flax) chromosomes. According to preliminary data, it provides a considerably more...