Rebound syndrome after teriflunomide cessation in a patient with multiple sclerosis

We report a case of relapsing remitting multiple sclerosis (RRMS) with severe rebound syndrome 12weeks following discontinuation of teriflunomide therapy. The patient developed severe clinical relapses with significant increase in the number of brain and spine magnetic resonance imaging (MRI) lesion...

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Bibliographic Details
Published inJournal of the neurological sciences Vol. 380; pp. 79 - 81
Main Authors Yamout, Bassem I, Said, Marianne, Hannoun, Salem, Zeineddine, Maya, Massouh, Joelle, Khoury, Samia J
Format Report
LanguageEnglish
Published 15.09.2017
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Summary:We report a case of relapsing remitting multiple sclerosis (RRMS) with severe rebound syndrome 12weeks following discontinuation of teriflunomide therapy. The patient developed severe clinical relapses with significant increase in the number of brain and spine magnetic resonance imaging (MRI) lesions. She responded well to intravenous and oral steroids and was later maintained on rituximab.
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ISSN:1878-5883
DOI:10.1016/j.jns.2017.07.014