Anaphylactic reaction to tranexamic acid in an adolescent undergoing posterior spinal fusion

Tranexamic acid is an anti-fibrinolytic agent frequently used in pediatric surgery. Common side effects include nausea, flushing, and headache, but in rare instances, it may produce anaphylaxis; with only one previously reported case in a 72-year-old man. We report a case of a delayed anaphylactic r...

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Published inPaediatric anaesthesia Vol. 27; no. 7; pp. 774 - 775
Main Authors Chiem, Jennifer, Ivanova, Iskra, Parker, Andrew, Krengel, Walter, Jimenez, Nathalia
Format Report
LanguageEnglish
Published 01.07.2017
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Summary:Tranexamic acid is an anti-fibrinolytic agent frequently used in pediatric surgery. Common side effects include nausea, flushing, and headache, but in rare instances, it may produce anaphylaxis; with only one previously reported case in a 72-year-old man. We report a case of a delayed anaphylactic reaction in a pediatric patient undergoing posterior spine fusion; and discuss the intraoperative management of the acute event, immunologic confirmation, and subsequent anesthetic approach.
Bibliography:ObjectType-Case Study-2
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SourceType-Reports-1
ObjectType-Report-1
ISSN:1460-9592
DOI:10.1111/pan.13141