Mild access to planar-chiral ortho-condensed aromatic ferrocenes viagold(i)-catalyzed cycloisomerization of ortho-alkynylaryl ferrocenes

An efficient approach to (R sub(p)) planar-chiral tri- and tetracyclic ortho-condensed aromatic ferrocenes was developed through the enantioselective cationic Au(i)-catalyzed cycloisomerization, in the presence of bidentate phosphine ligand (R)-DTBM-Segphos, from readily available ortho-alkynylaryl...

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Published inChemical communications (Cambridge, England) Vol. 52; no. 38; pp. 6419 - 6422
Main Authors Urbano, Antonio, Hernandez-Torres, Gloria, del Hoyo, Ana M, Martinez-Carrion, Alicia, Carmen Carreno, M
Format Journal Article
LanguageEnglish
Published 01.05.2016
Subjects
Cationic
Ferrocenes
Isomerization
Ligands
Phosphines
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Summary:An efficient approach to (R sub(p)) planar-chiral tri- and tetracyclic ortho-condensed aromatic ferrocenes was developed through the enantioselective cationic Au(i)-catalyzed cycloisomerization, in the presence of bidentate phosphine ligand (R)-DTBM-Segphos, from readily available ortho-alkynylaryl ferrocenes under very mild conditions (11 examples, up to 92% yield and 93% ee).
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ISSN:1359-7345
1364-548X
DOI:10.1039/c6cc02624a