A Prospective Clinical Trial of Treatment Models on Malignant Ovarian Germ Cell Tumor Patients

• Published in: Zhongliu fangzhi yanjiu Vol. 43; no. 3
• Main Authors: Lin, Jiajing, Zeng, Dingyuan, He, Hongying, Tan, Guangping, Lan, Ying, Jiang, Fuyan, Sheng, Shuting
• Format: Journal Article
• Language: Chinese
• Published: 01.01.2016
• ISSN: 1000-8578

Objective To evaluate the therapeutic value of conservative surgery for malignant ovarian germ cell tumor (MOGCT), to provide scientific evidence for choosing reasonable treatment model on MOGCT patients. Methods We conducted a multi-center, prospective clinical trial. Patients with MOGCT were allocated into conservative surgery group (n=33) and extensive surgery group (n=36). We evaluated the two treatment models by the outcomes of health economics, surgical safety, regular menstruation rate, pregnancy and effectiveness. Results (1) Health economics: the average initial hospital stays of the conservative surgery group and extensive surgery group were 16.27 and 19.91d, respectively; the average initial hospital costs were 16 603.11 and 24 701.58 RMB, respectively (P<0.05). (2) Surgical safety: there were statistical differences between the conservative surgery group and extensive surgery group in the average time of operation, the average recovery time of intestinal tract (P<0.05); there was no significant di