One-pot synthesis of N-heterocycles by tandem carbamoylationaoxidative bromolactamization of I-alkenylmagnesium bromide
An addition reaction of I-alkenylmagnesium bromide with p-toluenesulfonyl isocyanate and consecutive oxidative cyclization with iodobenzene diacetate afforded brominated lactams in one-pot. An imine was also applicable to a one-pot synthesis of terminally brominated cyclic amine.
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Published in | Tetrahedron letters Vol. 54; no. 32; pp. 4313 - 4315 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
01.08.2013
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Subjects | |
Online Access | Get full text |
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Summary: | An addition reaction of I-alkenylmagnesium bromide with p-toluenesulfonyl isocyanate and consecutive oxidative cyclization with iodobenzene diacetate afforded brominated lactams in one-pot. An imine was also applicable to a one-pot synthesis of terminally brominated cyclic amine. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 content type line 23 ObjectType-Feature-2 |
ISSN: | 0040-4039 |
DOI: | 10.1016/j.tetlet.2013.06.002 |