A novel one-pot and efficient procedure for the synthesis of 3H-spiro[isobenzofuran-1,6'-pyrrolo[2,3-d]pyrimidin e]-2',3,4',5'-tetraones

• Published in: Tetrahedron letters Vol. 51; no. 44; pp. 5807 - 5809
• Main Authors: Mohammadizadeh, Mohammad Reza, Bahramzadeh, Mojtaba, Taghavi, SZainabkhatoon
• Format: Journal Article
• Language: English
• Published: 03.11.2010
• Subjects: Cleavage; Ninhydrin; Synthesis (chemistry); Tetrahedrons

A novel and practical one-pot procedure is described for the preparation of several new of 3H-spiro[isobenzofuran-1,6'-pyrrolo[2,3-d]pyrimidine]-2',3, 4',5'-tetraones based on the addition reaction of ninhydrin and 6-aminouracils followed by oxidative cleavage of their correspond...