A novel one-pot and efficient procedure for the synthesis of 3H-spiro[isobenzofuran-1,6'-pyrrolo[2,3-d]pyrimidin e]-2',3,4',5'-tetraones

A novel and practical one-pot procedure is described for the preparation of several new of 3H-spiro[isobenzofuran-1,6'-pyrrolo[2,3-d]pyrimidine]-2',3, 4',5'-tetraones based on the addition reaction of ninhydrin and 6-aminouracils followed by oxidative cleavage of their correspond...

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Bibliographic Details
Published inTetrahedron letters Vol. 51; no. 44; pp. 5807 - 5809
Main Authors Mohammadizadeh, Mohammad Reza, Bahramzadeh, Mojtaba, Taghavi, SZainabkhatoon
Format Journal Article
LanguageEnglish
Published 03.11.2010
Subjects
Cleavage
Ninhydrin
Synthesis (chemistry)
Tetrahedrons
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Summary:A novel and practical one-pot procedure is described for the preparation of several new of 3H-spiro[isobenzofuran-1,6'-pyrrolo[2,3-d]pyrimidine]-2',3, 4',5'-tetraones based on the addition reaction of ninhydrin and 6-aminouracils followed by oxidative cleavage of their corresponding dihydroxyindenopyrrolopyrimidines.
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ISSN:0040-4039
DOI:10.1016/j.tetlet.2010.08.113