Effects of Corylus avellana in Acetaminophen and CCl sub(4) Induced Toxicosis

Our study investigated the effects of Corylus avellana extract on acetaminophen and carbon tetrachloride intoxicated liver of young rats. Hepatocytolysis was determined by measuring the level of serum transaminases (GPT and GOT), steatosis by Sudan black staining, histological structures by hamatoxy...

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Published inPhytotherapy research Vol. 13; no. 2; pp. 120 - 123
Main Authors Rusu, MA, Bucur, N, Puica, C, Tamas, M
Format Journal Article
LanguageEnglish
Published 01.03.1999
Subjects
Corylus avellana
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Summary:Our study investigated the effects of Corylus avellana extract on acetaminophen and carbon tetrachloride intoxicated liver of young rats. Hepatocytolysis was determined by measuring the level of serum transaminases (GPT and GOT), steatosis by Sudan black staining, histological structures by hamatoxylineosin staining and the activity of enzymes such as SDH, GtDH, G-6-Pase and ATPase. Comparatively, the most serious lesions appeared in CCl sub(4) intoxication. Corylus avellana extract had some beneficial effects in CCl sub(4) toxicosis: it reduced hepatocytolysis as well as histological lesions and returned the activity of some enzymes to normal values.
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ISSN:0951-418X